Z's Curiosity Lab

Z's Curiosity Lab

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Reflecting on My 2025 AI Predictions: Hits, Misses, and Surprises

Reflecting on My 2025 AI Predictions: Hits, Misses, and Surprises

I scored each of my 2025 AI predictions against what actually happened, with examples and links. The average came out around 8.9 out of 10, and a couple of them overstated the pace.

New mini-series: future tech that exists today

A short video series on future tech that already exists, just unevenly distributed: driverless rides, flying taxis, lab-grown meat, humanoid robots in factories, drone delivery and brain implants.

The 6 Levels of Awareness (and where you fit)

The 6 Levels of Awareness (and where you fit)

Scott Adams' "Levels of Awareness" framework, level by level, and what it says about why some people get stuck while others pull off the impossible.

Not having a quest is making you stressed. Here's the science.

Not having a quest is making you stressed. Here's the science.

People with a strong sense of purpose report less stress and stay more positive when things get hard. What the research shows, and what you can do with it.

5 AI Bombshells from Last Week: Gemini's Glow-Up & More

5 AI Bombshells from Last Week: Gemini's Glow-Up & More

Gemini 3 and four other AI releases from one busy week, from hurricane forecasts to 3D photo editing.

A Cancer Drug 20,000 Times More Effective, With Zero Side Effects?

A Cancer Drug 20,000 Times More Effective, With Zero Side Effects?

Northwestern researchers rebuilt an old, harsh chemotherapy drug with spherical nucleic acids. The animal results in leukemia were dramatic. What that means, and what it doesn't mean yet.

What 72 hours without food does to your immune system

What 72 hours without food does to your immune system

Research on prolonged fasting found that a few days without food can trigger immune stem cell regeneration. What happens in the body, and what it means for you.

100 invites left to Z's Curiosity Lab Discord

Z's Curiosity Lab has a Discord server. It's small, here's what has already happened there, and how to grab one of the remaining invites.

NEW RESEARCH - Your Cells Are Forgetting What They're Living For - And That's Why You're Aging

NEW RESEARCH - Your Cells Are Forgetting What They're Living For - And That's Why You're Aging

A computational biology study in Advanced Science argues that aging isn't cells breaking down. It's cells losing track of what they're supposed to be doing.

Scientists Just Made Old Monkeys Young Again - Here's What It Means

Scientists Just Made Old Monkeys Young Again - Here's What It Means

A Cell study from September 2025 reports the first broad rejuvenation in primates, using human stem cells engineered with a stronger version of the longevity gene FOXO3.

This will be the story you tell in 10 years

This will be the story you tell in 10 years

Derek Sivers on why circumstances don't change your happiness for long, and a way to look at what's happening now as the story you'll tell in ten years.

Scientists Found the Brain's "Aging Switch" (And How to Turn It Off!)

Scientists Found the Brain's "Aging Switch" (And How to Turn It Off!)

Researchers traced some age-related memory slips to a single protein gone rogue in the brain. What they found, and how they tried to switch it off.

GPT-5 is here. What you need to know.

GPT-5 is here. What you need to know.

GPT-5 is less a model than a product: several models behind a router that decides which one answers you. What changed, and what it means for how you use it.

This AI Robot Just Performed Surgery on Its Own (And It Was Flawless)

This AI Robot Just Performed Surgery on Its Own (And It Was Flawless)

A Johns Hopkins robot that learned surgery from videos removed a gallbladder with no human help, and got it right every time. How it worked and what comes next.

What I Told Non-AI Folks About Medicine Blew Their Minds

What I Told Non-AI Folks About Medicine Blew Their Minds

I've been talking about AI with people outside the field. The medical uses surprised them most, including the ones who work in medicine. Here's what I told them.

The Shadow Qualities You're Hiding From Yourself and How to Uncover Them

The Shadow Qualities You're Hiding From Yourself and How to Uncover Them

Carl Jung's "golden shadow": the strengths you hide from yourself, why they hold creatives and founders back, and how to find yours.

My friends asked me what I do when I'm overwhelmed, so...

My friends asked me what I do when I'm overwhelmed, so...

I was trying to do my wind down routine - gotta keep that sleep score up, amirite? - and my mind felt like a beehive at its peak. It wasn't a great sign... Several friends confided last 2 weeks they are feeling overwhelmed with everything on their table. And the

3-in-3 is becoming Z's Curiosity Lab

Hey there, curious minds 👋 Big news: 3-in-3 is becoming Z's Curiosity Lab. Don't panic. Your weekly dose of fascinating discoveries isn't going anywhere. We're just giving it a name that better reflects what we've become. What's

She Cured Her Depression in 5 Days with SAINT?

She Cured Her Depression in 5 Days with SAINT?

Thing 1 - She Cured Her Depression in 5 Days? Kate couldn't even get out of bed to pee. That's when she knew it was going to be a bad day. For years, the Blueprint co-founder had been trapped in what she calls "the numbness&

How CERN turned Lead into Gold - For Real!

How CERN turned Lead into Gold - For Real!

Thing 1 - Scientists at CERN Just Turned Lead into Gold Ancient alchemists would weep with joy. Physicists at CERN's ALICE experiment transformed lead into gold! ALICE stands for A Large Ion Collider Experiment. (Gotta give it to them, it's a cool acronym). It is one of

🧠 Brain-on-a-chip gets a body!

🧠 Brain-on-a-chip gets a body!

Thing 1 - Brain-on-a-chip gets a body Scientists in China, from Tianjin University and the Southern University of Science and Technology, developed a robot that's guided by a lab-grown human brain organoid!! As bonkers as it sounds, this is indeed a tiny, simplified version of

The Urban Legend That Rewrote the Law + 2 other things

The Urban Legend That Rewrote the Law + 2 other things

Thing 1 - The Urban Legend That Rewrote the Law It started with Halloween. Not from lack of candy. From fear. In the 1960s and 70s, parents across America suddenly started X-raying candy bars and inspecting apples like they were defusing bombs. Why?? The infamous urban legend of razor blades

The Science of Vibes: How Your Brain Tunes to the Room ⋆ AI of the week ⋆ Real Growth

The Science of Vibes: How Your Brain Tunes to the Room ⋆ AI of the week ⋆ Real Growth

Thing 1 - The Science of Vibes: How Your Brain Tunes to the Room Have you ever walked into a room and instantly felt the vibes were off? There's some basis for it in neuroscience. Your brain indeed does syncs with others around you through something called "inter-

Here's how they "de-extincted" a Dire Wolf

Here's how they "de-extincted" a Dire Wolf

Thing 1 - Here's how they "de-extincted" a Dire Wolf Or "how to make a dire wolf (in 7 easy steps)" Bringing back a dire wolf isn't sci-fi anymore. Here’s how it went down: 1. Find the fossils. First, you

What 105,000 Lives Taught Us About Longevity ⋆ AI of the week ⋆ Unlearning Creativity

What 105,000 Lives Taught Us About Longevity ⋆ AI of the week ⋆ Unlearning Creativity

Thing 1 - What 105,000 Lives Taught Us About Longevity When it comes to aging well, most people think it's all about luck. But a 30-year study tracking over 105,000 people says otherwise. Researchers from the Nurses' Health Study and the Health Professionals Follow-Up